About Enhancer
| Enhancer ID: | E_01_0291 |
| Species: | human |
| Position : | chr17:31933934-31935934   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 30700785 |
| Enhancer experiment: | ChIP-seq,Gateway Recombination cloning,EMSAs,HADDOCK Modeling |
| Enhancer experiment description: | PRC2 is composed of four main subunits; Suppressor of Zeste 12 (SUZ12), Retinoblastoma-Associated Protein 46/48 (RbAp46/48) |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | PRC2 is composed of four main subunits; Suppressor of Zeste 12 (SUZ12), Retinoblastoma-Associated Protein 46/48 (RbAp46/48) |
About TF
| TF name : | SUZ12 |
| TF experiment: | ChIP-seq,Gateway Recombination cloning,EMSAs,HADDOCK Modeling |
| TF experiment description: | PRC2 is composed of four main subunits; Suppressor of Zeste 12 (SUZ12), Retinoblastoma-Associated Protein 46/48 (RbAp46/48) |
About Function
| Enhancer function : | PRC2 is composed of four main subunits; Suppressor of Zeste 12 (SUZ12), Retinoblastoma-Associated Protein 46/48 (RbAp46/48) |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
PRC2 is composed of four main subunits; Suppressor of Zeste 12 (SUZ12), Retinoblastoma-Associated Protein 46/48 (RbAp46/48) |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| SUZ12 | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| SUZ12 | Oxidative Stress Induced Senescence | reactome | 120 |
| SUZ12 | PKMTs methylate histone lysines | reactome | 64 |
| SUZ12 | PRC2 methylates histones and DNA | reactome | 71 |
| SUZ12 | Hs_Interactome_of_polycomb_repressive_complex_2_(PRC2)_WP2916_88672 | wikipathways | 15 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene