About Enhancer
| Enhancer ID: | E_01_0129 |
| Species: | human |
| Position : | chr5:151027281-151029281   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Systemic lupus erythematosus |
| Pubmed ID: | 31804013 |
| Enhancer experiment: | Dual luciferase reporter assay, electrophoretic mobility shift assay, QRT PCR, Western blot, and pulldown |
| Enhancer experiment description: | Hypomorphic TNIP1 expression results from the combined concordant and opposing effects of multiple risk variants carried on the TNIP1 risk haplotype, with the strongest regulatory effect in B lymphoid lineage cells. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Hypomorphic TNIP1 expression results from the combined concordant and opposing effects of multiple risk variants carried on the TNIP1 risk haplotype, with the strongest regulatory effect in B lymphoid lineage cells. |
About TF
| TF name : | TNIP1 |
| TF experiment: | ??????????????????qRT-PCR?Western blot?pulldown |
| TF experiment description: | Hypomorphic TNIP1 expression results from the combined concordant and opposing effects of multiple risk variants carried on the TNIP1 risk haplotype, with the strongest regulatory effect in B lymphoid lineage cells. |
About Function
| Enhancer function : | Hypomorphic TNIP1 expression results from the combined concordant and opposing effects of multiple risk variants carried on the TNIP1 risk haplotype, with the strongest regulatory effect in B lymphoid lineage cells. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Hypomorphic TNIP1 expression results from the combined concordant and opposing effects of multiple risk variants carried on the TNIP1 risk haplotype, with the strongest regulatory effect in B lymphoid lineage cells. |
About SNP
| SNP ID: | -- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene