About Enhancer
| Enhancer ID: | E_01_0116 |
| Species: | human |
| Position : | chr15:42735912-42737912   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Gliomas |
| Pubmed ID: | 31858557 |
| Enhancer experiment: | Transfection, QRT PCR, Western blot, flow cytometry, Transwell, dual luciferase reporter assay |
| Enhancer experiment description: | Circ-TTBK2/miR-520b/EZH2 axis modulated cell proliferation, apoptosis, and invasion in glioma cell lines, and might serve as potential targets for glioma diagnosis and therapy. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Circ-TTBK2/miR-520b/EZH2 axis modulated cell proliferation, apoptosis, and invasion in glioma cell lines, and might serve as potential targets for glioma diagnosis and therapy. |
About TF
| TF name : | TTBK2 |
| TF experiment: | ???qRT-PCR?Western Blot???????Transwell?????????? |
| TF experiment description: | Circ-TTBK2/miR-520b/EZH2 axis modulated cell proliferation, apoptosis, and invasion in glioma cell lines, and might serve as potential targets for glioma diagnosis and therapy. |
About Function
| Enhancer function : | Circ-TTBK2/miR-520b/EZH2 axis modulated cell proliferation, apoptosis, and invasion in glioma cell lines, and might serve as potential targets for glioma diagnosis and therapy. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Circ-TTBK2/miR-520b/EZH2 axis modulated cell proliferation, apoptosis, and invasion in glioma cell lines, and might serve as potential targets for glioma diagnosis and therapy. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| TTBK2 | Anchoring of the basal body to the plasma membrane | reactome | 97 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene