About Enhancer
| Enhancer ID: | E_01_0094 |
| Species: | human |
| Position : | chr5:51380063-51382063   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Congenital heart disease |
| Pubmed ID: | 31914083 |
| Enhancer experiment: | -- |
| Enhancer experiment description: | ISL1 promotes cardiomyocyte differentiation and plays important roles in heart development. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | ISL1 promotes cardiomyocyte differentiation and plays important roles in heart development. |
About TF
| TF name : | ISL1(ISLET1,Isl-1) |
| TF experiment: | -- |
| TF experiment description: | ISL1 promotes cardiomyocyte differentiation and plays important roles in heart development. |
About Function
| Enhancer function : | ISL1 promotes cardiomyocyte differentiation and plays important roles in heart development. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
ISL1 promotes cardiomyocyte differentiation and plays important roles in heart development. |
About SNP
| SNP ID: | rs1017 |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| ISL1 | Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | reactome | 13 |
| ISL1 | Hs_Neural_Crest_Differentiation_WP2064_79263 | wikipathways | 40 |
| ISL1 | Hs_Heart_Development_WP1591_90186 | wikipathways | 28 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene