About Enhancer
| Enhancer ID: | E_01_0080 |
| Species: | human |
| Position : | chr10:52311442-52313442   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Osteoporosis |
| Pubmed ID: | 31963554 |
| Enhancer experiment: | QPCR, Western blot, immunofluorescence, luciferase assay, chromatin immunoprecipitation assay |
| Enhancer experiment description: | Taken together, these observations suggest that 1,25D3 promotes the mineralization of osteoblasts through activation of DKK1 followed by an increase of C/EBP?. |
About Target gene
| Target gene : | DKK1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Taken together, these observations suggest that 1,25D3 promotes the mineralization of osteoblasts through activation of DKK1 followed by an increase of C/EBP?. |
About TF
| TF name : | -- |
| TF experiment: | qPCR?Western Blot?????????????????????? |
| TF experiment description: | Taken together, these observations suggest that 1,25D3 promotes the mineralization of osteoblasts through activation of DKK1 followed by an increase of C/EBP?. |
About Function
| Enhancer function : | Taken together, these observations suggest that 1,25D3 promotes the mineralization of osteoblasts through activation of DKK1 followed by an increase of C/EBP?. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Taken together, these observations suggest that 1,25D3 promotes the mineralization of osteoblasts through activation of DKK1 followed by an increase of C/EBP?. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene