About Enhancer
| Enhancer ID: | E_01_0072 |
| Species: | human |
| Position : | chr13:27958465-27960465   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Esophageal diseases |
| Pubmed ID: | 28442495 |
| Enhancer experiment: | Western blot |
| Enhancer experiment description: | CDX2, a transcription factor required to form intestinal epithelium, is a target of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) signalling, which can be inhibited by aspirin. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | CDX2, a transcription factor required to form intestinal epithelium, is a target of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) signalling, which can be inhibited by aspirin. |
About TF
| TF name : | CDX2(CDX-3/AS,CDX3,CDX2) |
| TF experiment: | Western blot |
| TF experiment description: | CDX2, a transcription factor required to form intestinal epithelium, is a target of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) signalling, which can be inhibited by aspirin. |
About Function
| Enhancer function : | CDX2, a transcription factor required to form intestinal epithelium, is a target of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) signalling, which can be inhibited by aspirin. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
CDX2, a transcription factor required to form intestinal epithelium, is a target of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) signalling, which can be inhibited by aspirin. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CDX2 | POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | reactome | 10 |
| CDX2 | Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | reactome | 20 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene