About Enhancer
| Enhancer ID: | E_01_0032 |
| Species: | mouse |
| Position : | chr6:47504530-47506530   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Ovarian carcinoma |
| Pubmed ID: | 29233846 |
| Enhancer experiment: | Immunofluorescence,Western blot,RNA-seq ,qRTPCR,ChIP |
| Enhancer experiment description: | Ezh2 is the catalytic subunit containing a SET domain, which harbors the active site for histone H3 trimethylation on lysine 27 (H3K27me3), although Suz12 and Eed association is needed for optimal enzymatic activity8. |
About Target gene
| Target gene : | Ezh2 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Ezh2 is the catalytic subunit containing a SET domain, which harbors the active site for histone H3 trimethylation on lysine 27 (H3K27me3), although Suz12 and Eed association is needed for optimal enzymatic activity8. |
About TF
| TF name : | -- |
| TF experiment: | Immunofluorescence,Western blot,RNA-seq ,qRTPCR,ChIP |
| TF experiment description: | Ezh2 is the catalytic subunit containing a SET domain, which harbors the active site for histone H3 trimethylation on lysine 27 (H3K27me3), although Suz12 and Eed association is needed for optimal enzymatic activity8. |
About Function
| Enhancer function : | Ezh2 is the catalytic subunit containing a SET domain, which harbors the active site for histone H3 trimethylation on lysine 27 (H3K27me3), although Suz12 and Eed association is needed for optimal enzymatic activity8. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Ezh2 is the catalytic subunit containing a SET domain, which harbors the active site for histone H3 trimethylation on lysine 27 (H3K27me3), although Suz12 and Eed association is needed for optimal enzymatic activity8. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene