Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01979
Species: Homo sapiens
Position : chr6:162856700-162856970
Year: 2025
Title: Massively parallel reporter assays and mouse transgenic assays provide correlated and complementary information about neuronal enhancer activity.
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
PMID:  40404660
Tissue: brain
Tissue Ontology ID: UBERON:0000955
Cell Source: iPSC-derived excitatory neurons
Cell Type: excitatory neuron
Experiment Type: Enhancer activity assay, TF binding assay
High Throughput Method: ChIP-seq; ATAC-seq; RNA-seq; MPRA
Low Throughput Method: Transgenic Reporter Assay, qRT-PCR; Reporter assay; Transgenic mouse enhancer assay
About Target Gene
Target gene : QKI
About TF
TF name : RORB
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
RORB Nuclear Receptor transcription pathway reactome 51
Enhancer Associated Network
Overlapping Enhancers (hg38) 1 found
Enhancer ID Position Tissue Cell Disease
E_01978 chr6:162856700-162856970 brain excitatory neuron NA
Expression of Target Genes for the Enhancer