Comprehensive information about experimentally validated enhancers
| Enhancer ID: | E_01978 |
| Species: | Homo sapiens |
| Position : | chr6:162856700-162856970 |
| Year: | 2025 |
| Title: | Massively parallel reporter assays and mouse transgenic assays provide correlated and complementary information about neuronal enhancer activity. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 40404660 |
| Tissue: | brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | iPSC-derived excitatory neurons |
| Cell Type: | excitatory neuron |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | ChIP-seq; ATAC-seq; RNA-seq; MPRA |
| Low Throughput Method: | Transgenic Reporter Assay, qRT-PCR; Reporter assay; Transgenic mouse enhancer assay |
| Target gene : | QKI |
| TF name : | CTCF |
| Regulatory State : | Active |
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01979 | chr6:162856700-162856970 | brain | excitatory neuron | NA |