Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01976
Species: Homo sapiens
Position : chr6:97306500-97306770
Year: 2025
Title: Massively parallel reporter assays and mouse transgenic assays provide correlated and complementary information about neuronal enhancer activity.
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
PMID:  40404660
Tissue: brain
Tissue Ontology ID: UBERON:0000955
Cell Source: iPSC-derived excitatory neurons
Cell Type: excitatory neuron
Experiment Type: Enhancer activity assay, TF binding assay
High Throughput Method: ChIP-seq; ATAC-seq; RNA-seq; MPRA
Low Throughput Method: Transgenic Reporter Assay; RT-RT-qPCR; Reporter assay; Transgenic mouse enhancer assay
About Target Gene
Target gene : GPR63
About TF
TF name : CDX1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
CDX1 Regulation of nuclear beta catenin signaling and target gene transcription pid 80
Enhancer Associated Network
Overlapping Enhancers (hg38) 1 found
Enhancer ID Position Tissue Cell Disease
E_01977 chr6:97306500-97306770 brain excitatory neuron NA
Expression of Target Genes for the Enhancer