About Enhancer
| Enhancer ID: | E_01973 |
| Species: | Homo sapiens |
| Position : | chr12:6607234-6609134   |
| Year: | 2025 |
| Title: | SWI/SNF complex-mediated ZNF410 cooperative binding maintains chromatin accessibility and enhancer activity. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 40158221 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | erythroid lineage cell |
| Cell Ontology ID: | CL:0000764 |
| Experiment Type: | Enhancer activity assay; TF binding assay; Functional perturbation assay |
| High Throughput Method: | ATAC-seq; ChIP-seq (ZNF410; H3K27ac; H3K4me3; H3K9me3); RNA-seq |
| Low Throughput Method: | Luciferase reporter assay; CRISPR/Cas9 proximal enhancer deletion; CRISPRi (dCas9-KRAB); ChIP-qPCR; RT-qPCR |
About Target Gene
| Target gene : | CHD4 |
About TF
| TF name : | ZNF410 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer