About Enhancer
| Enhancer ID: | E_01938 |
| Species: | Homo sapiens |
| Position : | chr16:28930687-28931032   |
| Year: | 2026 |
| Title: | Nucleotide-resolution mapping of regulatory elements via allelic readout of tiled base editing. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 41771871 |
| Tissue: | prostate gland |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | LNCaP |
| CVCL ID: | CVCL_0395 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay; Endogenous enhancer perturbation; TF binding assay; Disease-variant functional analysis |
| High Throughput Method: | ChIP-seq, ATAC-seq, RNA-seq; RNA-seq |
| Low Throughput Method: | CRISPR Knockout, Luciferase Reporter Assay, ChIP-RT-qPCR, qRT-PCR; Site-directed/motif mutagenesis |
About Target Gene
| Target gene : | CD19 |
About TF
| TF name : | MYB |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| MYB | AP-1 transcription factor network | pid | 71 |
| MYB | C-MYB transcription factor network | pid | 87 |
| MYB | Factors involved in megakaryocyte development and platelet production | reactome | 111 |
| MYB | IL2 signaling events mediated by PI3K | pid | 38 |
| MYB | IL4-mediated signaling events | pid | 66 |
| MYB | Notch-mediated HES/HEY network | pid | 48 |
| MYB | Prolactin | netpath | 105 |
| MYB | Hs_Neural_Crest_Differentiation_WP2064_79263 | wikipathways | 40 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer