Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01931
Species: Homo sapiens
Position : chr8:23366136-23366992
Year: 2019
Title: A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  30612741
Tissue: pleural effusion
Tissue Ontology ID: UBERON:0000175
Cell Source: K-562
CVCL ID: CVCL_0004
Cell Type: malignant cell
Cell Ontology ID: CL:0001064
Experiment Type: Endogenous CRISPRi cis-regulatory perturbation; enhancer-gene mapping; singleton replication; Endogenous enhancer perturbation; Disease-variant functional analysis
High Throughput Method: Multiplexed dCas9-KRAB CRISPRi screen; single-cell RNA-seq; RNA-seq; eQTL analysis
Low Throughput Method: Singleton CRISPRi plus bulk RNA-seq; CRISPR-Cas9 endogenous deletion/editing
About Target Gene
Target gene : SLC25A37
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer