Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01836
Species: Homo sapiens
Position : chr6:45407433-45444666
Year: 2024
Title: Exploring the transcriptional cooperation between RUNX2 and its associated elncRNA RAIN.
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: thyroid gland carcinoma
PMID:  39271656
MONDO: MONDO:0015075
Tissue: thyroid gland
Tissue Ontology ID: UBERON:0002046
Cell Source: TPC-1
CVCL ID: CVCL_6298
Cell Type: malignant cell
Cell Ontology ID: CL:0001064
Experiment Type: RNA-chromatin association assay; Functional perturbation assay; In vivo functional validation
High Throughput Method: ChIRP-seq; RNA-seq; H3K4me1/H3K4me3/H3K27ac ChIP-seq
Low Throughput Method: qRT-PCR; RAIN CRISPRi; Western blot; In vivo phenotyping
About Target Gene
Target gene : RUNX2
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 1 found
Enhancer ID Position Tissue Cell Disease
E_01809 chr6:45407433-45444666 thyroid gland malignant cell thyroid gland carcinoma
Expression of Target Genes for the Enhancer