Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01747
Species: Homo sapiens
Position : chr6:31139519-31140167
Year: 2018
Title: The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  30590035
Cell Source: Human Primordial Germ Cell
Experiment Type: TF-binding/chromatin assay; Endogenous enhancer perturbation
High Throughput Method: ChIP-seq; ATAC-seq
Low Throughput Method: CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP; RT-qPCR/qPCR
About Target Gene
Target gene : POU5F1
About TF
TF name : TFAP2C
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
TFAP2C Validated transcriptional targets of TAp63 isoforms pid 54
Enhancer Associated Network
Overlapping Enhancers (hg19) 3 found
Enhancer ID Position Tissue Cell Disease
E_02653 chr6:31139599-31139921 embryo embryonic stem cell NA
E_02654 chr6:31139599-31139921 embryonic stem-cell culture embryonic stem cell NA
E_02663 chr6:31139599-31139921 NA NA NA
Expression of Target Genes for the Enhancer