Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01705
Species: Homo sapiens
Position : chr6:31140556-31141204
Year: 2018
Title: The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  30590035
Cell Source: Human Primordial Germ Cell
Experiment Type: TF-binding/chromatin assay; Chromatin interaction assay; Endogenous enhancer perturbation
High Throughput Method: ChIP-seq; ATAC-seq
Low Throughput Method: CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP; RT-qPCR/qPCR
About Target Gene
Target gene : POU5F1
About TF
TF name : TFAP2C
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
TFAP2C Validated transcriptional targets of TAp63 isoforms pid 54
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer