About Enhancer
| Enhancer ID: | E_01696 |
| Species: | Homo sapiens |
| Position : | chr3:134460112-134466940   |
| Year: | 2024 |
| Title: | Single cell variant to enhancer to gene map for coronary artery disease. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | coronary artery disorder |
| PMID: | 39606421 |
| MONDO: | MONDO:0005010 |
| Tissue: | coronary artery |
| Tissue Ontology ID: | UBERON:0001621 |
| Cell Source: | Human coronary artery tissue smooth muscle cell compartment |
| Cell Type: | smooth muscle cell of the coronary artery |
| Cell Ontology ID: | CL:0002592 |
| Experiment Type: | Variant-to-enhancer-to-gene mapping; Chromatin accessibility assay; Chromatin interaction assay; Enhancer activity profiling |
| High Throughput Method: | Single-nucleus Multiome RNA+ATAC-seq; snATAC-seq; genome-wide Hi-C; H3K27ac ChIP-seq (coronary artery reference integration); Hi-C |
| Low Throughput Method: | CRISPRi |
About Target Gene
| Target gene : | AMOTL2 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01740 | chr3:134460112-134466940 | coronary artery | smooth muscle cell of the coronary artery | coronary artery disorder |
Expression of Target Genes for the Enhancer