About Enhancer
| Enhancer ID: | E_01678 |
| Species: | Homo sapiens |
| Position : | chr7:54888020-54890020   |
| Year: | 2019 |
| Title: | Functional Enhancers Shape Extrachromosomal Oncogene Amplifications. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | glioblastoma |
| PMID: | 31761532 |
| MONDO: | MONDO:0018177 |
| Tissue: | brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | G361 glioblastoma patient-derived model |
| Cell Type: | glioblastoma cell |
| Cell Ontology ID: | CL:0001063 |
| Experiment Type: | Enhancer functional perturbation assay |
| High Throughput Method: | H3K27ac ChIP-seq; ATAC-seq; POLR2A ChIP-seq; RNA-seq |
| Low Throughput Method: | CRISPRi; RT-qPCR; Alamar Blue cell-viability assay |
About Target Gene
| Target gene : | EGFR |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer