About Enhancer
| Enhancer ID: | E_01676 |
| Species: | Homo sapiens |
| Position : | chr11:62864230-62864780   |
| Year: | 2022 |
| Title: | Chromatin state dynamics confers specific therapeutic strategies in enhancer subtypes of colorectal cancer. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | colorectal adenocarcinoma |
| PMID: | 34059508 |
| MONDO: | MONDO:0005008 |
| Tissue: | colon |
| Tissue Ontology ID: | UBERON:0001155 |
| Cell Source: | colorectal cancer tissues and cell lines |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Tumor-specific enhancer functional perturbation |
| High Throughput Method: | H3K27ac ChIP-seq; H3K4me1 ChIP-seq; H3K4me3 ChIP-seq; H3K79me2 ChIP-seq; H3K27me3 ChIP-seq; H3K9me3 ChIP-seq; RNA-seq |
| Low Throughput Method: | CRISPR/dCas9 epigenomic enhancer repression; proliferation assay |
About Target Gene
| Target gene : | FZD10 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer