Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01654
Species: Homo sapiens
Position : chr7:55085000-55090000
Year: 2019
Title: Functional Enhancers Shape Extrachromosomal Oncogene Amplifications.
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: glioblastoma
PMID:  31761532
MONDO: MONDO:0018177
Tissue: brain
Tissue Ontology ID: UBERON:0000955
Cell Source: GSC23
CVCL ID: CVCL_DR59
Cell Type: glioblastoma stem cell
Experiment Type: Enhancer perturbation assay
High Throughput Method: H3K27ac ChIP-seq; 4C-seq
Low Throughput Method: CRISPRi dCas9-KRAB; RT-qPCR; cell viability assay
About Target Gene
Target gene : EGFR
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 1 found
Enhancer ID Position Tissue Cell Disease
E_03278 chr7:54978916-55304142 breast malignant cell multiple cancer types
Expression of Target Genes for the Enhancer