Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01628
Species: Homo sapiens
Position : chr7:54932020-54934020
Year: 2019
Title: Functional Enhancers Shape Extrachromosomal Oncogene Amplifications.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: glioblastoma
PMID:  31761532
MONDO: MONDO:0018177
Tissue: brain
Tissue Ontology ID: UBERON:0000955
Cell Source: GBM3565 patient-derived glioblastoma model
Cell Type: glioblastoma cell
Cell Ontology ID: CL:0001063
Experiment Type: Enhancer activity assay; chromatin interaction assay; CRISPRi functional screen
High Throughput Method: H3K27ac ChIP-seq; ATAC-seq; RNA-seq; CRISPRi screen; 4C-seq
Low Throughput Method: RT-qPCR; FISH
About Target Gene
Target gene : EGFR
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_01630 chr7:54932020-54934020 brain glioblastoma cell glioblastoma
E_01679 chr7:54932020-54934020 brain glioblastoma cell glioblastoma
Expression of Target Genes for the Enhancer