About Enhancer
| Enhancer ID: | E_01619 |
| Species: | Homo sapiens |
| Position : | chr12:130610556-130610854   |
| Year: | 2022 |
| Title: | Chromatin state dynamics confers specific therapeutic strategies in enhancer subtypes of colorectal cancer. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | colorectal adenocarcinoma |
| PMID: | 34059508 |
| MONDO: | MONDO:0005008 |
| Tissue: | colon |
| Tissue Ontology ID: | UBERON:0001155 |
| Cell Source: | colorectal adenocarcinoma/adenoma/normal colon tissues |
| Cell Type: | epithelial cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Tumor-specific enhancer mapping; chromatin interaction assay; CRISPR epigenomic perturbation |
| High Throughput Method: | H3K27ac/H3K4me1/H3K4me3/H3K79me2/H3K27me3/H3K9me3 ChIP-seq; RNA-seq; H3K27ac HiChIP |
| Low Throughput Method: | dCas9-KRAB enhancer repression; H3K27ac ChIP-qPCR; 3C; RT-qPCR; proliferation assay |
About Target Gene
| Target gene : | FZD10 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer