About Enhancer
| Enhancer ID: | E_01513 |
| Species: | Homo sapiens |
| Position : | chr17:37879571-37880263   |
| Year: | 2018 |
| Title: | A novel HER2 gene body enhancer contributes to HER2 expression. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Breast Cancer |
| PMID: | 29035388 |
| MONDO: | MONDO:0007254 |
| Tissue: | blood / hematopoietic system |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; Endogenous enhancer perturbation; Disease-associated enhancer analysis |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP |
About Target Gene
| Target gene : | ERBB2 |
About TF
| TF name : | TFAP2C |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| TFAP2C | Validated transcriptional targets of TAp63 isoforms | pid | 54 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer