Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01502
Species: Homo sapiens
Position : chr7:117038917-117040917
Year: 2016
Title: Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  26673704
Cell Source: Caco-2
CVCL ID: CVCL_0025
Experiment Type: TF-binding/chromatin assay; Chromatin interaction assay; Endogenous enhancer perturbation
Low Throughput Method: CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP; 4C; RT-qPCR/qPCR
About Target Gene
Target gene : CFTR
About TF
TF name : FOXA1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
FOXA1 AndrogenReceptor netpath 167
FOXA1 Direct p53 effectors pid 141
FOXA1 FOXA1 transcription factor network pid 45
FOXA1 FOXA2 and FOXA3 transcription factor networks pid 45
FOXA1 Hs_Endoderm_Differentiation_WP2853_88152 wikipathways 62
Enhancer Associated Network
Overlapping Enhancers (hg19) 4 found
Enhancer ID Position Tissue Cell Disease
E_04497 chr7:117011495-117063767 skin fibroblast Cystic Fibrosis
E_01501 chr7:117038917-117040917 NA NA NA
E_01503 chr7:117038917-117040917 NA NA NA
E_01504 chr7:117038917-117040917 NA NA NA
Expression of Target Genes for the Enhancer