About Enhancer
| Enhancer ID: | E_01323 |
| Species: | Homo sapiens |
| Position : | chr3:46453226-46459225   |
| Year: | 2025 |
| Title: | Enhancer transcription profiling reveals an enhancer RNA-driven ferroptosis and new therapeutic opportunities in prostate cancer. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | prostate cancer |
| PMID: | 40082405 |
| MONDO: | MONDO:0008315 |
| Tissue: | prostate gland |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | LNCaP |
| CVCL ID: | CVCL_0395 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Functional perturbation assay, Enhancer activity assay, Chromatin interaction assay, TF binding assay; TF binding assay; Chromatin-state profiling |
| High Throughput Method: | ATAC-seq, RNA-seq, ChIP-seq, 3C-seq; RNA-seq; ATAC-seq; ChIP-seq |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot, FISH; ChIP |
About Target Gene
| Target gene : | LTF |
About TF
| TF name : | HNRNPF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| HNRNPF | FGFR2 alternative splicing | reactome | 27 |
| HNRNPF | pre-mRNA splicing | reactome | 135 |
| HNRNPF | Processing of Capped Intron-Containing Pre-mRNA | reactome | 37 |
| HNRNPF | Hs_MECP2_and_Associated_Rett_Syndrome_WP3584_91190 | wikipathways | 12 |
Enhancer Associated Network
Overlapping Enhancers (hg38)
3 found
Expression of Target Genes for the Enhancer