About Enhancer
| Enhancer ID: | E_01319 |
| Species: | Homo sapiens |
| Position : | chr6:12490000-12590000   |
| Year: | 2017 |
| Title: | A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression. |
| Genome Build: | hg19 |
| Enhancer Type: | Super-enhancer |
| Condition: | Disease |
| Disease Name: | Coronary Artery Disease,Migraine Headache,Cervical Artery Dissection,Fibromuscular Dysplasia,Hypertension |
| PMID: | 28753427 |
| Cell Source: | HUVEC |
| Experiment Type: | Enhancer activity assay; Chromatin interaction assay; Disease-associated enhancer analysis |
| High Throughput Method: | RNA-seq; 4C-seq |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay |
About Target Gene
| Target gene : | EDN1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer