About Enhancer
| Enhancer ID: | E_01276 |
| Species: | Homo sapiens |
| Position : | chr6:12852000-12853000   |
| Year: | 2017 |
| Title: | A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | coronary artery disease |
| PMID: | 28753427 |
| Tissue: | lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | BEAS-2B |
| CVCL ID: | CVCL_0168 |
| Cell Type: | bronchial epithelial cell |
| Cell Ontology ID: | CL:0002328 |
| Experiment Type: | Enhancer perturbation assay; Disease-variant functional analysis |
| High Throughput Method: | ChIP-seq, 4C-seq; GWAS |
| Low Throughput Method: | CRISPR Knockout, Luciferase Reporter Assay |
About Target Gene
| Target gene : | EDN1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer