About Enhancer
| Enhancer ID: | E_01177 |
| Species: | Homo sapiens |
| Position : | chr9:126770367-126771183   |
| Year: | 2020 |
| Title: | Accelerated evolution of an Lhx2 enhancer shapes mammalian social hierarchies. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 32238901 |
| Tissue: | brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq; RNA-seq; Hi-C; ATAC-seq |
| Low Throughput Method: | Luciferase Reporter Assay; Transgenic Reporter Assay; CRISPR Knockout; CRISPRi, qRT-PCR; Knock-in mouse |
About Target Gene
| Target gene : | LHX2 |
About TF
| TF name : | CTCF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer