Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01176
Species: Homo sapiens
Position : chr8:128804981-128806980
Year: 2021
Title: ecDNA hubs drive cooperative intermolecular oncogene expression.
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: colorectal carcinoma
PMID:  34819668
MONDO: MONDO:0024331
Tissue: colon
Tissue Ontology ID: UBERON:0001155
Cell Source: COLO 320DM
CVCL ID: CVCL_0219
Cell Type: malignant cell
Cell Ontology ID: CL:0001064
Experiment Type: Enhancer activity assay, Functional perturbation assay; Endogenous enhancer perturbation
High Throughput Method: ATAC-seq, ChIP-seq, Hi-C
Low Throughput Method: CRISPRi, Luciferase Reporter Assay, FISH, RT-RT-qPCR; CRISPRi
About Target Gene
Target gene : MYC
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 1 found
Enhancer ID Position Tissue Cell Disease
E_03876 chr8:126650000-129950000 colon malignant cell NA
Expression of Target Genes for the Enhancer