About Enhancer
| Enhancer ID: | E_01173 |
| Species: | Homo sapiens |
| Position : | chr3:111274001-111275000   |
| Year: | 2025 |
| Title: | Enhancer activation from transposable elements in extrachromosomal DNA. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | colorectal adenocarcinoma |
| PMID: | 41120733 |
| MONDO: | MONDO:0005008 |
| Tissue: | sigmoid colon |
| Tissue Ontology ID: | UBERON:0001159 |
| Cell Source: | COLO320DM |
| CVCL ID: | CVCL_0219 |
| Cell Type: | colon epithelial cell, adenocarcinoma-derived |
| Cell Ontology ID: | CL:0011108 |
| Experiment Type: | Enhancer activity assay; Functional perturbation assay; Chromatin interaction assay; Endogenous enhancer perturbation |
| High Throughput Method: | Hi-C; Nanopore ultra-long read sequencing; H3K27ac ChIP-seq; ATAC-seq; RNA-seq; CRISPRi screen |
| Low Throughput Method: | Luciferase reporter assay; CRISPRi dCas9-KRAB; CRISPR-CATCH; RNA-FISH; ORCA imaging; RT-qPCR; CRISPRi; Reporter assay |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01182 | chr3:111274001-111275000 | sigmoid colon | colon epithelial cell, adenocarcinoma-derived | colorectal adenocarcinoma |
Expression of Target Genes for the Enhancer