Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01170
Species: Homo sapiens
Position : chr11:118540532-118575295
Year: 2015
Title: Functional analysis of the 11q23.3 glioma susceptibility locus implicates PHLDB1 and DDX6 in glioma susceptibility.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: glioma
PMID:  26610392
MONDO: MONDO:0021042
Tissue: brain
Tissue Ontology ID: UBERON:0000955
Cell Source: Normal Human Astrocyte
Experiment Type: Enhancer activity assay; Chromatin interaction assay; Genetic-variant functional analysis; Disease-associated enhancer analysis
Low Throughput Method: Luciferase reporter assay; Reporter assay; 3C
About Target Gene
Target gene : DDX6
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_01158 chr11:118559857-118561857 brain glioblastoma-like cell line malignant glioma
E_01168 chr11:118559857-118561857 brain astrocyte malignant glioma
Expression of Target Genes for the Enhancer