About Enhancer
| Enhancer ID: | E_01168 |
| Species: | Homo sapiens |
| Position : | chr11:118559857-118561857   |
| Year: | 2015 |
| Title: | Functional analysis of the 11q23.3 glioma susceptibility locus implicates PHLDB1 and DDX6 in glioma susceptibility. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | malignant glioma |
| PMID: | 26610392 |
| MONDO: | MONDO:0100342 |
| Tissue: | brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | hTERT-immortalized normal human astrocytes |
| Cell Type: | astrocyte |
| Cell Ontology ID: | CL:0000127 |
| Experiment Type: | Enhancer activity assay; Allele-specific functional assay; Chromatin-state assay; Chromatin interaction assay; Disease-variant functional analysis |
| High Throughput Method: | ENCODE H3K27ac/H3K4me1/H3K4me3/DHS/FAIRE-seq integration; GWAS |
| Low Throughput Method: | Luciferase enhancer scanning; allele-specific reporter assay; EMSA; 3C |
About Target Gene
| Target gene : | DDX6 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer