Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01132
Species: Homo sapiens
Position : chr8:98310330-98314427
Year: 2017
Title: A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: Small B Cell Lymphoma
PMID:  29045844
Tissue: blood / hematopoietic system
Tissue Ontology ID: UBERON:0000178
Cell Source: Mantle Cell Lymphoma (MCL)
Cell Type: B cell
Cell Ontology ID: CL:0000236
Experiment Type: TF-binding/chromatin assay; Chromatin interaction assay; Endogenous enhancer perturbation; Disease-associated enhancer analysis
High Throughput Method: ChIP-seq; 4C-seq
Low Throughput Method: ChIP-qPCR/ChIP; 4C; RT-qPCR/qPCR
About Target Gene
Target gene : MYC
About TF
TF name : POU2AF1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 3 found
Enhancer ID Position Tissue Cell Disease
E_01130 chr8:98310330-98314427 blood / hematopoietic system B cell Small B Cell Lymphoma
E_01131 chr8:98310330-98314427 blood / hematopoietic system B cell Small B Cell Lymphoma
E_01133 chr8:98310330-98314427 blood / hematopoietic system B cell Small B Cell Lymphoma
Expression of Target Genes for the Enhancer