About Enhancer
| Enhancer ID: | E_01123 |
| Species: | Homo sapiens |
| Position : | chr19:41868242-41871230   |
| Year: | 2020 |
| Title: | CRISPRi-mediated functional analysis of lung disease-associated loci at non-coding regions. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | asthma |
| PMID: | 32500120 |
| MONDO: | MONDO:0004979 |
| Tissue: | lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | A-549 |
| CVCL ID: | CVCL_0023 |
| Cell Type: | epithelial cell of lung |
| Cell Ontology ID: | CL:0000082 |
| Experiment Type: | Enhancer activity assay; Functional perturbation assay; Gene expression assay |
| High Throughput Method: | Hi-C; H3K27ac ChIP-seq; ChIP-seq; eQTL analysis |
| Low Throughput Method: | CRISPRi; RT-qPCR |
About Target Gene
| Target gene : | TMEM91 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01119 | chr19:41868242-41871230 | lung | epithelial cell of lung | asthma |
| E_01120 | chr19:41868242-41871230 | lung | epithelial cell of lung | chronic obstructive pulmonary disease |
| E_01121 | chr19:41868242-41871230 | lung | epithelial cell of lung | asthma |
| E_01122 | chr19:41868242-41871230 | lung | epithelial cell of lung | chronic obstructive pulmonary disease |
| E_01124 | chr19:41868242-41871230 | lung | epithelial cell of lung | chronic obstructive pulmonary disease |
Expression of Target Genes for the Enhancer