About Enhancer
| Enhancer ID: | E_01082 |
| Species: | Homo sapiens |
| Position : | chr10:89875711-89876693   |
| Year: | 2023 |
| Title: | Landscape of enhancer disruption and functional screen in melanoma cells. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | breast carcinoma |
| PMID: | 37904237 |
| MONDO: | MONDO:0004989 |
| Tissue: | breast |
| Tissue Ontology ID: | UBERON:0000310 |
| Cell Source: | T-47D |
| CVCL ID: | CVCL_0553 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq; ATAC-seq; CRISPRi Screen; whole-genome sequencing |
| Low Throughput Method: | Luciferase Reporter Assay; CRISPRi; CRISPRa; RT-RT-qPCR; Western blot; Cell Apoptosis Assay; Colony Formation Assay |
About Target Gene
| Target gene : | PTEN |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer