Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01072
Species: Homo sapiens
Position : chr15:99982353-99983277
Year: 2023
Title: Landscape of enhancer disruption and functional screen in melanoma cells.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: cutaneous melanoma
PMID:  37904237
MONDO: MONDO:0005012
Tissue: zone of skin
Tissue Ontology ID: UBERON:0000014
Cell Source: Melanoma cell line
Cell Type: melanoma cell
Experiment Type: Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay
High Throughput Method: HiChIP; ATAC-seq; ChIP-seq; RNA-seq; whole-genome sequencing
Low Throughput Method: Luciferase Reporter Assay; CRISPR Knockout; CRISPRi, 3C-seq, 4C-seq; RT-RT-qPCR; Western blot; CRISPRi
About Target Gene
Target gene : MEF2A
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer