About Enhancer
| Enhancer ID: | E_00977 |
| Species: | Homo sapiens |
| Position : | chr8:129543949-129554294   |
| Year: | 2016 |
| Title: | Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers. |
| Genome Build: | hg19 |
| Enhancer Type: | Super-enhancer |
| Condition: | Disease |
| Disease Name: | endometrial carcinoma |
| PMID: | 26656844 |
| MONDO: | MONDO:0002447 |
| Tissue: | endometrium |
| Tissue Ontology ID: | UBERON:0001295 |
| Cell Source: | Ishikawa |
| CVCL ID: | CVCL_2529 |
| Cell Type: | epithelial cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Super-enhancer profiling; Chromatin interaction assay; Copy-number amplification analysis; Endogenous enhancer perturbation |
| High Throughput Method: | H3K27ac ChIP-seq; p300 ChIP-seq; copy-number analysis |
| Low Throughput Method: | 3C-qPCR; RT-qPCR; CRISPR-Cas9 endogenous deletion/editing |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
3 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00939 | chr8:129543949-129554294 | uterus | malignant cell | endometrial carcinoma |
| E_00976 | chr8:129543949-129554294 | endometrium | malignant cell | endometrial carcinoma |
| E_05249 | chr8:129546728-129712179 | blood | B-lymphoblast/precursor B cell | B-cell acute lymphoblastic leukemia |
Expression of Target Genes for the Enhancer