Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00953
Species: Homo sapiens
Position : chr20:48997377-49019434
Year: 2016
Title: Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.
Genome Build: hg19
Enhancer Type: Super-enhancer
Condition: Disease
Disease Name: hepatocellular carcinoma
PMID:  26656844
MONDO: MONDO:0007256
Tissue: liver
Tissue Ontology ID: UBERON:0002107
Cell Source: Hep G2
CVCL ID: CVCL_0027
Cell Type: hepatocyte
Cell Ontology ID: CL:0000182
Experiment Type: Enhancer activity assay; TF-binding/chromatin assay; Chromatin interaction assay; Endogenous enhancer perturbation; Disease-associated enhancer analysis
High Throughput Method: ChIP-seq
Low Throughput Method: Luciferase reporter assay; Reporter assay; CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP; 3C; RT-qPCR/qPCR; RNAi/siRNA/shRNA
About Target Gene
Target gene : PARD6B
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_02876 chr20:48400000-49200000 breast malignant cell breast cancer
E_02877 chr20:48400000-49200000 breast malignant cell breast cancer
Expression of Target Genes for the Enhancer