About Enhancer
| Enhancer ID: | E_00760 |
| Species: | Homo sapiens |
| Position : | chr8:127898362-127899967   |
| Year: | 2016 |
| Title: | Systematic mapping of functional enhancer-promoter connections with CRISPR interference. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 27708057 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay; functional perturbation assay; chromatin interaction assay; Endogenous enhancer perturbation |
| High Throughput Method: | CRISPRi tiling screen; DNase-seq data integration; H3K27ac ChIP-seq data integration; in situ Hi-C data integration; ChIA-PET data integration |
| Low Throughput Method: | Individual dCas9-KRAB CRISPRi; RT-qPCR; plasmid-based reporter assay; competitive growth assay; CRISPRi |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer