Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00673
Species: Homo sapiens
Position : chr17:35447019-35447926
Year: 2020
Title: Noncoding Variants Connect Enhancer Dysregulation with Nuclear Receptor Signaling in Hematopoietic Malignancies.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: hematologic malignancy
PMID:  32188707
MONDO: MONDO:0021447
Tissue: blood
Tissue Ontology ID: UBERON:0000178
Cell Source: K-562
CVCL ID: CVCL_0004
Experiment Type: Enhancer activity assay; Functional perturbation assay
High Throughput Method: enCRISPRa screen; enCRISPRi screen; targeted resequencing
Low Throughput Method: CRISPR activation; CRISPR interference
About Target Gene
Target gene : ACACA
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_00551 chr17:35447019-35447926 bone marrow malignant cell hematopoietic malignancy
E_00552 chr17:35447019-35447926 bone marrow malignant cell hematopoietic malignancy
Expression of Target Genes for the Enhancer