Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00640
Species: Homo sapiens
Position : chr22:42411769-42414470
Year: 2015
Title: Functional characterization of CYP2D6 enhancer polymorphisms.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  25381333
Tissue: liver
Tissue Ontology ID: UBERON:0002107
Cell Source: Human Primary Hepatocytes
Cell Type: hepatocyte
Cell Ontology ID: CL:0000182
Experiment Type: Enhancer activity assay; TF-binding/chromatin assay; Chromatin interaction assay
Low Throughput Method: Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; 4C
About Target Gene
Target gene : CYP2D6
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 9 found
Enhancer ID Position Tissue Cell Disease
E_00275 chr22:42411333-42413643 liver hepatocyte NA
E_00639 chr22:42411544-42415106 liver hepatocyte NA
E_00151 chr22:42411693-42414130 liver epithelial cell NA
E_00152 chr22:42411693-42414130 liver NA NA
E_00274 chr22:42411693-42414130 liver hepatocyte NA
E_00382 chr22:42411693-42414130 liver hepatocyte NA
E_00412 chr22:42411693-42414130 liver hepatocyte NA
E_00413 chr22:42411693-42414130 liver hepatocyte NA
E_00414 chr22:42411693-42414130 liver hepatocyte NA
Expression of Target Genes for the Enhancer