About Enhancer
| Enhancer ID: | E_00603 |
| Species: | Homo sapiens |
| Position : | chr17:38022100-38022900   |
| Year: | 2016 |
| Title: | 17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | asthma |
| PMID: | 27848966 |
| MONDO: | MONDO:0004979 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Primary CD4+ T cells |
| Cell Type: | CD4-positive T cell |
| Cell Ontology ID: | CL:0000624 |
| Experiment Type: | Chromatin interaction assay, Enhancer activity assay, Gene expression assay |
| High Throughput Method: | 4C-seq; ChIP-seq; RNA-seq; DNase-seq; 4C |
| Low Throughput Method: | RT-qPCR; Flow cytometry; Cytokine ELISA |
About Target Gene
| Target gene : | ORMDL3 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00700 | chr17:38022212-38022898 | blood | naive thymus-derived CD4-positive alpha-beta T cell | asthma |
Expression of Target Genes for the Enhancer