About Enhancer
| Enhancer ID: | E_00508 |
| Species: | Homo sapiens |
| Position : | chr10:8287120-8287832   |
| Year: | 2020 |
| Title: | Noncoding Variants Connect Enhancer Dysregulation with Nuclear Receptor Signaling in Hematopoietic Malignancies. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | hematopoietic malignancy |
| PMID: | 32188707 |
| Tissue: | bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | MKPL-1 |
| CVCL ID: | CVCL_2116 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | High-throughput functional CRE perturbation screen; candidate enhancer annotation; Disease-variant functional analysis |
| High Throughput Method: | pooled enCRISPRi screen; pooled enCRISPRa screen; H3K27ac ChIP-seq; ATAC-seq |
| Low Throughput Method: | individual CRISPRi; CRISPR-Cas41 TF-binding-site deletion |
About Target Gene
| Target gene : | LINC00708 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer