About Enhancer
| Enhancer ID: | E_00451 |
| Species: | Homo sapiens |
| Position : | chr6:151953109-151955347   |
| Year: | 2016 |
| Title: | Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | breast carcinoma |
| PMID: | 27571262 |
| MONDO: | MONDO:0004989 |
| Tissue: | pleural effusion |
| Tissue Ontology ID: | UBERON:0000175 |
| Cell Source: | T-47D |
| CVCL ID: | CVCL_0553 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Functional perturbation assay; Enhancer activity assay |
| High Throughput Method: | DNase-seq; H3K27ac ChIP-seq |
| Low Throughput Method: | CRISPR-Cas9 enhancer deletion; RT-qPCR |
About Target Gene
| Target gene : | ESR1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
3 found
Expression of Target Genes for the Enhancer