About Enhancer
| Enhancer ID: | E_00378 |
| Species: | Homo sapiens |
| Position : | chr8:128919000-128920000   |
| Year: | 2018 |
| Title: | Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | breast carcinoma |
| PMID: | 29731168 |
| MONDO: | MONDO:0004989 |
| Tissue: | breast |
| Tissue Ontology ID: | UBERON:0000310 |
| Cell Source: | MDA-MB-231 |
| CVCL ID: | CVCL_0062 |
| Cell Type: | breast carcinoma epithelial cell |
| Experiment Type: | Enhancer activity; enhancer-promoter competition; endogenous perturbation |
| High Throughput Method: | ATAC-seq; H3K27ac ChIP-seq/HiChIP; RNA-seq |
| Low Throughput Method: | Luciferase reporter assay; CRISPRi; PVT1 promoter genome editing; RT-qPCR; Western blot |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer