SEdb 2.0
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Gene overview

Strategies/Algorithm: proximal Ensembl ID: ENSG00000133246
Gene: PRAM1 Gene type: protein_coding
Strand: - External links:
Genomic region: chr19:8490056-8502640 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_090800483 chr19:8390931-8488107 Sample_02_0908 Heart left ventricle_DCM_LV1262 483 29 2791 244 9 364 2638 RAB11B,HNRNPM,MARCH2,RAB11B-AS1,MIR4999,PRAM1,ZNF414,KANK3,ANGPTL4
SE_02_090100382 chr19:8390938-8487690 Sample_02_0901 Heart left ventricle_LV1471 382 24 2778 244 9 364 2570 RAB11B,HNRNPM,MARCH2,RAB11B-AS1,MIR4999,PRAM1,ZNF414,KANK3,ANGPTL4
SE_02_090900350 chr19:8390941-8472452 Sample_02_0909 Heart left ventricle_DCM_LV1264 350 17 2335 203 5 322 2057 RAB11B,HNRNPM,MARCH2,RAB11B-AS1,MIR4999,PRAM1,ZNF414,KANK3,ANGPTL4
SE_02_039601506 chr19:8391229-8456514 Sample_02_0396 Skin NHEK-D 1506 13 1893 171 4 154 1705 RAB11B,MARCH2,HNRNPM,PRAM1,KANK3,ANGPTL4,2-MAR
SE_02_082600720 chr19:8397540-8454685 Sample_02_0826 Stomach gastric tumor 720 17 1652 147 4 119 1643 RAB11B,HNRNPM,MARCH2,RAB11B-AS1,MIR4999,ANGPTL4,PRAM1
SE_02_095001048 chr19:8411032-8460512 Sample_02_0950 Umbilical vein HUVEC_WT 1048 16 1381 95 3 125 962 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,ANGPTL4,PRAM1
SE_02_087500918 chr19:8413126-8458253 Sample_02_0875 Peripheral blood Peripheral blood-derived mast cells 918 12 1260 89 3 120 956 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,ANGPTL4,PRAM1
SE_02_076201749 chr19:8415136-8460992 Sample_02_0762 Podocyte podocyte_CTL 1749 10 1288 84 4 113 814 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,PRAM1
SE_02_116900698 chr19:8415847-8466732 Sample_02_1169 Biliary H69_TGF beta_16h_2 698 17 1403 95 4 220 1018 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,ZNF414,PRAM1
SE_02_104801232 chr19:8415848-8453893 Sample_02_1048 Peripheral blood CD4+ cell_UNTREATED 1232 6 1071 77 3 64 752 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,PRAM1
SE_02_098901355 chr19:8417712-8484628 Sample_02_0989 Kidney kidney cortex_WT 1355 25 1881 148 7 250 1292 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,ZNF414,PRAM1
SE_02_129700292 chr19:8421708-8490042 Sample_02_1297 Lung lung 292 23 1928 149 9 310 1852 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,ZNF414,PRAM1
SE_02_116600734 chr19:8422741-8465925 Sample_02_1166 Biliary H69_TGF beta_16h_1 734 13 1150 80 3 202 749 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,ZNF414,PRAM1
SE_02_076600690 chr19:8422874-8460499 Sample_02_0766 Ovary PEO1 690 19 1026 69 2 100 592 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,PRAM1,RPS28,ZNF414,CD320,NDUFA7,ADAMTS10,ANGPTL4
SE_02_105000317 chr19:8422916-8459484 Sample_02_1050 Highly metastatic osteosarcoma MG63-3_DMSO 317 12 998 69 2 100 592 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,PRAM1
SE_02_081800791 chr19:8423032-8460500 Sample_02_0818 Ovary High-grade serous ovarian cancer 791 13 1023 68 2 100 592 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,PRAM1
SE_02_067200655 chr19:8423044-8488419 Sample_02_0672 Endometrium endometrium cancer_DSG 655 15 1822 140 7 275 1580 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,ZNF414,PRAM1
SE_02_116800761 chr19:8423084-8464595 Sample_02_1168 Biliary H69_TGF Vehicle_2 761 16 1118 73 3 181 693 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,ZNF414,PRAM1
SE_02_116700748 chr19:8423094-8462440 Sample_02_1167 Biliary H69_TGF Vehicle_1 748 13 1065 70 3 127 602 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,PRAM1
SE_02_148200511 chr19:8434538-8478628 Sample_02_1482 Bone POE 511 18 1211 92 4 222 794 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,ZNF414,PRAM1
SE_02_143301211 chr19:8437782-8470138 Sample_02_1433 Bone A673 STAG2 null 1211 6 862 65 3 210 640 HNRNPM,MARCH2,RAB11B,RAB11B-AS1,MIR4999,ZNF414,PRAM1
SE_01_003300416 chr19:8441005-8458968 Sample_01_0033 Embryo H9 416 4 483 32 2 75 185 HNRNPM,MARCH2,PRAM1
SE_02_003801074 chr19:8441639-8454371 Sample_02_0038 Embryo DE 1074 4 329 25 2 30 123 HNRNPM,MARCH2,PRAM1
SE_02_074501292 chr19:8441788-8453747 Sample_02_0745 Embryo ES derived cardiac progenitor cells_day7 1292 2 305 23 2 30 123 HNRNPM,MARCH2,PRAM1
SE_01_005400288 chr19:8444081-8489375 Sample_01_0054 Haematopoietic and lymphoid tissue OCI-LY3 288 4 1278 102 8 278 1296 HNRNPM,ZNF414,MARCH2,PRAM1
SE_02_004300567 chr19:8444109-8453507 Sample_02_0043 Embryo endodermal CyT49_ES_D2 567 6 248 19 2 29 123 HNRNPM,MARCH2,PRAM1
SE_02_075200449 chr19:8444121-8456563 Sample_02_0752 Embryo ES-derived progenitors_DE_wild type 449 2 341 27 2 43 185 HNRNPM,MARCH2,PRAM1
SE_02_075500760 chr19:8444171-8456837 Sample_02_0755 Embryo ES-derived progenitors_DE FOXA2 -/- 760 1 351 27 2 45 185 HNRNPM,MARCH2,PRAM1
SE_02_148000833 chr19:8444200-8471463 Sample_02_1480 Bone MHH-ES-1 833 9 738 56 3 208 524 HNRNPM,ZNF414,MARCH2,PRAM1
SE_02_138800838 chr19:8444924-8462368 Sample_02_1388 Peripheral blood JB6_ALK+ 838 6 464 30 3 98 143 HNRNPM,MARCH2,PRAM1
SE_02_074601200 chr19:8446882-8489367 Sample_02_0746 Embryo ES derived primitive cardiomyocite_day15 1200 24 1186 101 8 254 1173 HNRNPM,ZNF414,MARCH2,PRAM1
SE_02_158300677 chr19:8447701-8480561 Sample_02_1583 Fetal lung IMR90_empty_GM 677 17 881 78 5 189 496 HNRNPM,ZNF414,MARCH2,PRAM1
SE_00_004800258 chr19:8486426-8490010 Sample_00_0048 Embryo neuronal stem cell originated from H1 258 4 113 7 2 31 443 HNRNPM,ZNF414,PRAM1
SE_02_077501914 chr19:8504635-8526294 Sample_02_0775 Pancreas EndoC-BH1_SE 1914 3 706 111 3 75 1424 MYO1F,ZNF414,PRAM1
SE_02_064200761 chr19:8505607-8527124 Sample_02_0642 Mammary gland MDA-MB-436_20C paclitaxel 761 4 708 106 3 80 1610 MYO1F,ZNF414,PRAM1
SE_02_139400641 chr19:8505615-8518729 Sample_02_1394 Lymph node anaplastic large cell lymphoma cells_ALK+#208 641 3 407 85 1 55 907 ZNF414,PRAM1
SE_02_004400638 chr19:8505636-8526721 Sample_02_0044 Embryo endodermal CyT49_ES_D5 638 4 698 106 3 76 1524 MYO1F,ZNF414,PRAM1
SE_02_050300411 chr19:8505640-8527015 Sample_02_0503 Esophagus KYSE140_1 411 4 707 106 3 80 1585 MYO1F,ZNF414,PRAM1
SE_02_051500415 chr19:8505652-8527015 Sample_02_0515 Esophagus KYSE140 415 4 706 106 3 80 1585 MYO1F,ZNF414,PRAM1
SE_02_104500255 chr19:8505702-8537701 Sample_02_1045 Peripheral blood CD4+ CD7- cells_CTCL992 255 15 1042 124 3 104 2154 MYO1F,ZNF414,PRAM1
SE_02_104000439 chr19:8505705-8529540 Sample_02_1040 Peripheral blood CD4+ cells_CTCL1126 439 6 770 109 3 86 1710 MYO1F,ZNF414,PRAM1
SE_02_059200482 chr19:8505868-8519013 Sample_02_0592 PBMCs adult CD4+CD25hiCD127lo regulatory T cells 482 3 404 85 1 55 907 ZNF414,PRAM1
SE_02_092901246 chr19:8505870-8526356 Sample_02_0929 Mid-gestation placenta trophoblast__CytT 1246 5 680 104 3 74 1432 MYO1F,ZNF414,PRAM1,MARCH2,ADAMTS10,RAB11B
SE_02_104901332 chr19:8510970-8515605 Sample_02_1049 Peripheral blood CD4+ cell_ROMI 1332 1 140 32 1 53 740 ZNF414,PRAM1
SE_02_104901849 chr19:8517793-8522949 Sample_02_1049 Peripheral blood CD4+ cell_ROMI 1849 1 176 16 2 18 410 MYO1F,ZNF414,PRAM1
SE_02_103602520 chr19:8525952-8527184 Sample_02_1036 Mammary gland HCC70_XY018 2520 1 34 2 0 6 189 MYO1F,ZNF414,PRAM1
SE_02_002400326 chr19:8536776-8576132 Sample_02_0024 Blood CD56+ Natural Killer cells donor A 326 26 1241 88 1 89 1427 MYO1F,ZNF414,ADAMTS10,PRAM1
SE_02_082100132 chr19:8548419-8578540 Sample_02_0821 Haematopoietic and lymphoid tissue SET-2_WT_GSK-LSD1 132 7 928 61 1 70 894 MYO1F,ZNF414,ADAMTS10,PRAM1
Genomic distribution of SEs associated with PRAM1
Genome Browser

The strength of the tissue affected by the gene

Expression of PRAM1

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)