Gene overview

Strategies/Algorithm: proximal Ensembl ID: ENSG00000126822
Gene: PLEKHG3 Gene type: protein_coding
Strand: + External links:
Genomic region: chr14:64704102-64750249 Genome Browser:

Super-enhancer search result of gene-based

SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_047500738 chr14:64603212-64655955 Sample_02_0475 Induced hepatocyte-like cells hepatocyte-like cells 738 10 1383 110 1 70 0 PLEKHG3
SE_02_017201007 chr14:64610151-64655621 Sample_02_0172 Lung IMR-90_quiescent 1007 9 1228 97 1 62 0 PLEKHG3
SE_02_020900544 chr14:64610342-64654982 Sample_02_0209 Lung MRC-5_MRC5_1DPT 544 8 1203 96 1 60 0 PLEKHG3
SE_02_011400146 chr14:64611170-64686530 Sample_02_0114 Mammary gland CAL51 146 24 2024 182 4 81 0 PLEKHG3
SE_02_043800289 chr14:64611271-64682826 Sample_02_0438 Bone HOS 289 34 1915 170 3 71 0 PLEKHG3
SE_02_039700343 chr14:64611328-64664158 Sample_02_0397 Mammary gland CAL51-MCF-7 343 11 1451 126 1 59 0 PLEKHG3
SE_02_139800036 chr14:64612449-64684765 Sample_02_1398 Bone U2OS_siNC 36 28 1950 177 3 69 0 PLEKHG3
SE_00_003101058 chr14:64618783-64655649 Sample_00_0031 Placenta placenta 1058 5 1027 89 1 32 0 PLEKHG3,PPP1R36,ZBTB25
SE_02_044100183 chr14:64622259-64655564 Sample_02_0441 Bone M112 183 15 944 88 1 32 0 PLEKHG3
SE_02_043900639 chr14:64622288-64654733 Sample_02_0439 Bone Hu09 639 8 921 86 1 29 0 PLEKHG3
SE_02_103501279 chr14:64625742-64684072 Sample_02_1035 Mammary gland HCC70_Vehicle 1279 22 1617 160 3 49 0 PLEKHG3
SE_03_000800602 chr14:64627733-64674193 Sample_03_0008 Lung A549_dexamethasone_7h 602 5 1314 143 2 31 0 PLEKHG3
SE_03_001500471 chr14:64627919-64682927 Sample_03_0015 Lung A549_dexamethasone_8h 471 9 1529 153 3 39 0 PLEKHG3
SE_02_001101011 chr14:64627969-64682775 Sample_02_0011 Kidney A-498_wtVHL 1011 17 1520 153 3 39 0 PLEKHG3
SE_02_047400749 chr14:64628041-64664852 Sample_02_0474 Fibroblast umbilical cord Fibroblast 749 10 1069 112 1 27 0 PLEKHG3
SE_02_126400586 chr14:64628135-64667100 Sample_02_1264 Bone Im-GCT-4072_G34W KO 586 14 1123 122 1 31 0 PLEKHG3
SE_02_111300022 chr14:64628158-64665843 Sample_02_1113 Bone U2OS 22 17 1092 114 1 27 0 PLEKHG3
SE_02_111500025 chr14:64628185-64667072 Sample_02_1115 Liver HepG2 25 14 1123 121 1 31 0 PLEKHG3
SE_02_046601046 chr14:64628213-64658140 Sample_02_0466 Adipose visceral adipocytes 1046 19 870 91 1 27 0 PLEKHG3
SE_02_126600514 chr14:64628253-64663343 Sample_02_1266 Bone Im-GCT-4072_G34W-repair_WT_E3 514 14 1030 105 1 27 0 PLEKHG3
SE_01_006600721 chr14:64628268-64663935 Sample_01_0066 Smooth muscle smooth-muscle-cell 721 7 1045 106 1 27 0 PLEKHG3
SE_02_126500458 chr14:64628301-64667030 Sample_02_1265 Bone Im-GCT-4072_G34W-repair_WT_D6 458 14 1120 121 1 31 0 PLEKHG3
SE_02_076600572 chr14:64628335-64683911 Sample_02_0766 Ovary PEO1 572 23 1545 155 3 48 0 PLEKHG3
SE_02_137901258 chr14:64628346-64654774 Sample_02_1379 Pancreas Pancreatic_tumor_associated_fibroblasts_PS1_untreated 1258 6 772 76 1 24 0 PLEKHG3
SE_02_124100817 chr14:64628393-64654910 Sample_02_1241 Skin MCC26_virus_negative 817 11 775 76 1 25 0 PLEKHG3
SE_02_113400029 chr14:64628457-64665023 Sample_02_1134 Bone U2OS-interphase 29 20 1062 113 1 27 0 PLEKHG3
SE_02_081601849 chr14:64628647-64659521 Sample_02_0816 Ovary Clear cell ovarian cancer 1849 12 906 97 1 24 0 PLEKHG3
SE_02_083901220 chr14:64628712-64655466 Sample_02_0839 Embryo hNPCs_K755R/+ 1220 4 785 78 1 24 0 PLEKHG3
SE_02_028100024 chr14:64631463-64684762 Sample_02_0281 Bone U2OS 24 4 1498 157 3 42 0 PLEKHG3
SE_02_113600678 chr14:64631801-64664646 Sample_02_1136 Bone U2OS-anaphase/telophase 678 12 967 108 1 20 0 PLEKHG3
SE_02_093000718 chr14:64632687-64662010 Sample_02_0930 Mid-gestation placenta trophoblast__SynT 718 17 889 100 1 19 0 PLEKHG3,ZBTB25
SE_02_070100212 chr14:64636067-64656874 Sample_02_0701 Bone David_TC32 212 10 622 77 1 19 0 PLEKHG3
SE_02_032601072 chr14:64636497-64657806 Sample_02_0326 Liver hepatocytes_d3 1072 4 637 81 1 19 0 PLEKHG3
SE_02_032701081 chr14:64636557-64657457 Sample_02_0327 Liver hepatocytes_d6 1081 5 626 81 1 19 0 PLEKHG3
SE_02_087600342 chr14:64637415-64669469 Sample_02_0876 Muscle SMS-CTR_CASZ1b_Ctrl 342 9 930 119 1 21 0 PLEKHG3
SE_02_055700512 chr14:64637642-64654750 Sample_02_0557 iPSCs WT hiPSC#1 512 4 521 66 1 14 0 PLEKHG3
SE_02_076000892 chr14:64639672-64684663 Sample_02_0760 Ovary BIN-67_SMARCA4 892 16 1254 147 3 39 0 PLEKHG3
SE_02_061300645 chr14:64644610-64682738 Sample_02_0613 Liposarcoma MLPS_T1 645 14 1070 121 3 25 0 PLEKHG3
SE_02_072500461 chr14:64673585-64683498 Sample_02_0725 Mammary gland MCF10A-YAP5SA_ctrl 461 5 253 13 1 16 0 PLEKHG3
SE_02_101000126 chr14:64682597-64693045 Sample_02_1010 Brain Lateral temporal lobe_3T_AD 126 2 298 30 2 21 0 PLEKHG3
SE_00_002300600 chr14:64744432-64765045 Sample_00_0023 Embryo mesenchymal-stem-cell 600 3 594 44 1 55 1142 SPTB,PLEKHG3
SE_02_092300611 chr14:64745151-64780267 Sample_02_0923 Heart fetal heart_PCW10_12522 611 7 1108 131 4 151 2447 SPTB,MIR7855,PLEKHG3
SE_01_009400172 chr14:64745179-64881040 Sample_01_0094 Gastrocnemius medialis gastrocnemius medialis_54y 172 37 4043 590 14 707 4583 SPTB,MIR7855,CHURC1,PLEKHG3
SE_02_092100606 chr14:64745213-64780330 Sample_02_0921 Heart embryonic heart_CS22 606 9 1107 131 4 150 2447 SPTB,MIR7855,PLEKHG3
SE_02_126900793 chr14:64745247-64763497 Sample_02_1269 Bone Im-GCT-4072_G34W-repair_WT_A4 793 3 516 36 1 47 1118 SPTB,MIR7855,PLEKHG3
SE_00_002900548 chr14:64745534-64764835 Sample_00_0029 Ovary ovary 548 10 554 42 1 52 1118 SPTB,PLEKHG3
SE_02_111000636 chr14:64745620-64764963 Sample_02_1110 Other HGrC1 636 4 553 43 1 54 1118 SPTB,MIR7855,PLEKHG3
SE_02_104100182 chr14:64747138-64771871 Sample_02_1041 Peripheral blood CD4+ cells_CTCL1135 182 8 768 82 2 79 1566 SPTB,MIR7855,PLEKHG3
SE_02_021500081 chr14:64748449-64778444 Sample_02_0215 Skin NHEK_siGRHL3 81 6 968 116 4 131 1781 SPTB,PLEKHG3
SE_02_139900539 chr14:64752736-64764306 Sample_02_1399 Bone U2OS_siMLL3.1 539 7 361 30 1 22 147 SPTB,MIR7855,PLEKHG3
SE_02_028100039 chr14:64753298-64766187 Sample_02_0281 Bone U2OS 39 1 402 38 1 28 147 SPTB,PLEKHG3
SE_02_139800550 chr14:64753511-64764886 Sample_02_1398 Bone U2OS_siNC 550 3 349 30 1 28 109 SPTB,MIR7855,PLEKHG3
SE_02_076000924 chr14:64753875-64764989 Sample_02_0760 Ovary BIN-67_SMARCA4 924 3 328 31 1 24 29 SPTB,MIR7855,PLEKHG3
SE_02_024000486 chr14:64754393-64765053 Sample_02_0240 Colon V429_2 486 5 309 30 1 24 0 SPTB,PLEKHG3
SE_02_002100654 chr14:64754459-64763329 Sample_02_0021 Colon V429 654 2 252 22 1 17 0 SPTB,PLEKHG3

Genomic distribution of SEs associated with PLEKHG3

The strength of the tissue affected by the gene


Expression of PLEKHG3