SEdb 2.0
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Gene overview

Strategies/Algorithm: proximal Ensembl ID: ENSG00000229391
Gene: HLA-DRB6 Gene type: transcribed_unprocessed_pseudogene
Strand: - External links:
Genomic region: chr6:32552713-32560022 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_01_002000766 chr6:32518946-32533595 Sample_01_0020 Blood B-cell 766 6 886 967 2 16 299 HLA-DRB5,HLA-DRB6
SE_00_000500367 chr6:32525680-32533516 Sample_00_0005 Blood B-cell 367 4 310 297 2 6 81 HLA-DRB5,HLA-DRB6
SE_01_002000001 chr6:32574008-32642736 Sample_01_0020 Blood B-cell 1 12 5556 4357 553 81 943 HLA-DQA1,HLA-DRB1,HLA-DRB5,HLA-DQB1,HLA-DRB6
SE_02_008100287 chr6:32580137-32643175 Sample_02_0081 Blood Monocyte-derived_dendritic_cells 287 9 5207 3992 551 82 906 HLA-DQA1,HLA-DRB1,HLA-DRB5,HLA-DQB1,HLA-DRB6
SE_02_131200093 chr6:32583577-32627831 Sample_02_1312 Brain hMGLs_WT 93 14 3420 2617 458 49 206 HLA-DRB1,HLA-DQA1,HLA-DRB6,HLA-DQB1
SE_02_131700136 chr6:32584063-32627683 Sample_02_1317 Brain hMGLs_SORL1-KO 136 10 3379 2566 458 49 197 HLA-DRB1,HLA-DQA1,HLA-DRB6,HLA-DQB1
SE_02_131500086 chr6:32584087-32643116 Sample_02_1315 Brain hMGLs_INPP5D SNP 86 16 4954 3720 543 77 683 HLA-DQA1,HLA-DRB1,HLA-DRB6,HLA-DQB1
SE_02_131400054 chr6:32584258-32642659 Sample_02_1314 Brain hMGLs_TREM2-KO 54 16 4882 3662 541 56 573 HLA-DQA1,HLA-DRB1,HLA-DRB6,HLA-DQB1
SE_02_142900606 chr6:32584586-32622655 Sample_02_1429 Blood GM12878_WT 606 5 2875 2142 371 29 83 HLA-DRB1,HLA-DQA1,HLA-DRB6,HLA-DQB1,TAP1,HLA-DQA2
SE_02_138600100 chr6:32584603-32639781 Sample_02_1386 Peripheral blood Karpas-299_ALK+ 100 15 4519 3368 521 40 277 HLA-DQA1,HLA-DRB1,HLA-DRB6,HLA-DQB1
SE_02_010000126 chr6:32585283-32629223 Sample_02_0100 Peripheral blood Macrophages_GM-CSF_72h 126 8 3402 2522 462 34 83 HLA-DRB1,HLA-DQB1,HLA-DQA1,HLA-DRB6
SE_02_010200237 chr6:32585350-32635638 Sample_02_0102 Peripheral blood Macrophages_GM-CSF_72h_IL4 237 11 4006 2906 484 34 83 HLA-DRB1,HLA-DQB1,HLA-DQA1,HLA-DRB6
SE_02_002500003 chr6:32585564-32642271 Sample_02_0025 Blood CD19donorA 3 23 4750 3517 540 50 460 HLA-DQA1,HLA-DRB1,HLA-DQB1,HLA-DRB6
SE_00_000500002 chr6:32585711-32640685 Sample_00_0005 Blood B-cell 2 8 4554 3361 527 41 315 HLA-DQA1,HLA-DRB1,HLA-DQB1,HLA-DRB6
SE_02_021300134 chr6:32585920-32642788 Sample_02_0213 Burkitts lymphoma of the left maxilla Raji_JQ1 134 6 4782 3530 540 61 526 HLA-DQA1,HLA-DRB1,HLA-DQB1,HLA-DRB6
SE_01_002400671 chr6:32586082-32628677 Sample_01_0024 Blood CD14-positive-monocyte 671 6 3320 2428 459 34 83 HLA-DRB1,HLA-DQB1,HLA-DQA1,HLA-DRB6
SE_02_010300183 chr6:32586240-32634657 Sample_02_0103 Peripheral blood Macrophages_GM-CSF_72h_TNF-a_PGE2_Pam3CSK4 183 8 3865 2761 482 34 83 HLA-DRB1,HLA-DQB1,HLA-DQA1,HLA-DRB6
SE_00_002700140 chr6:32586273-32638778 Sample_00_0027 Blood natural-killer-cell 140 10 4281 3123 513 35 160 HLA-DQA1,HLA-DRB1,HLA-DQB1,HLA-DRB6
SE_01_003000086 chr6:32586314-32640518 Sample_01_0030 Haematopoietic and lymphoid tissue blood GM12878 86 5 4493 3302 526 41 315 HLA-DQA1,HLA-DRB1,HLA-DQB1,HLA-DRB6,HLA
SE_02_115200396 chr6:32587003-32640405 Sample_02_1152 Lymphoma RL_WT_gRNA1 396 6 4413 3255 525 41 315 HLA-DQA1,HLA-DRB1,HLA-DRB6,HLA-DQB1
SE_00_003900736 chr6:32587631-32626742 Sample_00_0039 Spleen spleen_3y 736 9 3017 2241 449 31 83 HLA-DRB1,HLA-DQB1,HLA-DQA1,HLA-DRB6
SE_02_038700053 chr6:32593081-32642198 Sample_02_0387 Lymph node CD19+_B_cells_nhl_FL1-2 53 35 4041 3034 515 40 361 HLA-DQA1,HLA-DRB1,HLA-DQB1,HLA-DRB6
SE_02_131600359 chr6:32600668-32627539 Sample_02_1316 Brain hMGLs_TREM2-R47H 359 12 2142 1629 362 21 0 HLA-DRB1,HLA-DQA1,HLA-DRB6,HLA-DQB1
SE_02_131800181 chr6:32600674-32628761 Sample_02_1318 Brain hMGLs_SORL1-A528T 181 10 2244 1685 366 22 0 HLA-DRB1,HLA-DQA1,HLA-DRB6,HLA-DQB1
SE_02_131300225 chr6:32600685-32639499 Sample_02_1313 Brain hMGLs_CD33_SNP 225 14 3314 2473 423 26 160 HLA-DQA1,HLA-DRB1,HLA-DRB6,HLA-DQB1
SE_02_048800267 chr6:32601297-32623091 Sample_02_0488 Bone marrow HSCe_74y_CD34+,CD38-,Lineage- 267 6 1697 1277 278 17 0 HLA-DRB1,HLA-DQA1,HLA-DRB6,HLA-DQB1
SE_02_078200442 chr6:32601640-32634730 Sample_02_0782 Blood MEC1 442 9 2724 1970 380 22 0 HLA-DRB1,HLA-DQA1,HLA-DRB6,HLA-DQB1
SE_02_073600166 chr6:32602565-32639605 Sample_02_0736 Blood Pt24_leukemia cell_THZ1 166 20 3186 2382 408 26 167 HLA-DQA1,HLA-DRB1,HLA-DRB6,HLA-DQB1
SE_01_004000316 chr6:32602675-32690995 Sample_01_0040 Haematopoietic and lymphoid tissue Karpas-422 316 12 7344 5199 549 83 1495 HLA-DQB1,HLA-DQA1,HLA-DRB1,HLA-DRB6
SE_02_143000943 chr6:32603550-32610580 Sample_02_1430 Blood Kasumi-3_mock-infected 943 2 521 414 60 17 0 HLA-DRB1,HLA-DQA1,HLA-DRB6
SE_02_122000699 chr6:32603646-32626590 Sample_02_1220 Bone marrow JJN3 699 8 1862 1402 330 19 0 HLA-DRB1,HLA-DQA1,HLA-DRB6,HLA-DQB1
SE_02_021200120 chr6:32603959-32670226 Sample_02_0212 Burkitts lymphoma of the left maxilla Raji_DMSO 120 12 5827 4449 508 83 1495 HLA-DQB1,HLA-DQA1,HLA-DRB1,HLA-DRB6
SE_02_049000033 chr6:32604081-32623045 Sample_02_0490 Bone marrow HSCe_68y_CD34+,CD38-,Lineage- 33 7 1509 1115 262 17 0 HLA-DRB1,HLA-DQA1,HLA-DRB6,HLA-DQB1
SE_02_038600049 chr6:32604235-32623910 Sample_02_0386 Lymph node CD19+_B_cells_FL1-2 49 7 1572 1164 289 19 0 HLA-DRB1,HLA-DQB1,HLA-DQA1,HLA-DRB6
Genomic distribution of SEs associated with HLA-DRB6
Genome Browser

The strength of the tissue affected by the gene

Expression of HLA-DRB6

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)