SEdb 2.0
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Gene overview

Strategies/Algorithm: proximal Ensembl ID: ENSG00000023445
Gene: BIRC3 Gene type: protein_coding
Strand: + External links:
Genomic region: chr11:102317450-102339403 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_029400001 chr11:102107307-102289037 Sample_02_0294 Pancreatic L3-6_DMSO 1 14 5111 241 15 237 1275 YAP1,BIRC3
SE_02_017200555 chr11:102136471-102288748 Sample_02_0172 Lung IMR-90_quiescent 555 23 4237 184 14 161 593 YAP1,BIRC3
SE_02_127900210 chr11:102137130-102290247 Sample_02_1279 Bone Mesenchymal stem cells 210 45 4250 188 14 161 593 YAP1,BIRC3
SE_02_042000037 chr11:102168275-102277438 Sample_02_0420 Pectoralis major muscle LHCN-M2_dox_6h 37 22 3049 119 12 131 548 YAP1,BIRC3
SE_02_000500049 chr11:102213906-102273325 Sample_02_0005 Cervical cervical-cancer_KDM5C 49 4 1598 59 5 57 401 YAP1,BIRC3
SE_02_076200621 chr11:102219893-102295015 Sample_02_0762 Podocyte podocyte_CTL 621 13 2067 80 3 65 401 YAP1,BIRC3
SE_02_086700964 chr11:102220057-102288781 Sample_02_0867 Bone marrow Bone marrow derived hMSC_d0 964 30 1887 69 3 65 401 YAP1,BIRC3
SE_02_136200303 chr11:102220844-102270846 Sample_02_1362 Bladder UMUC1_sonic_pSIN-puro H1146A/E1148A-mutant UTX 303 16 1338 50 2 43 401 YAP1,BIRC3
SE_02_154000464 chr11:102220982-102270514 Sample_02_1540 Nasopharyngeal HK1 464 12 1324 48 2 43 401 YAP1,BIRC3
SE_02_061900053 chr11:102221438-102270649 Sample_02_0619 Head and Neck HPV+ HNSCC_SCC-047 53 13 1317 48 2 43 401 YAP1,BIRC3
SE_02_143400118 chr11:102224221-102288087 Sample_02_1434 Trophoblast trophoblast stem cells 118 10 1740 60 3 54 361 YAP1,BIRC3
SE_02_016700816 chr11:102224804-102270844 Sample_02_0167 Mammary gland HCC1954_LCC2 816 6 1210 40 2 33 361 YAP1,BIRC3
SE_02_103100078 chr11:102241242-102293524 Sample_02_1031 Head and neck SCC1 contol 78 30 1434 45 2 23 0 BIRC3
SE_02_048001213 chr11:102242412-102271536 Sample_02_0480 Gingival epithelial HGEP 1213 9 761 18 1 1 0 BIRC3
SE_02_136100956 chr11:102243700-102270879 Sample_02_1361 Bladder UMUC1_sonic_pSIN-puro_WTUTX 956 8 707 18 1 1 0 BIRC3
SE_02_094800050 chr11:102244279-102270785 Sample_02_0948 Pharyng Detroit562 50 4 689 17 1 1 0 BIRC3
SE_02_010500809 chr11:102244305-102280515 Sample_02_0105 Skin neonatal_keratinocytes 809 5 985 29 1 18 0 BIRC3
SE_02_006300891 chr11:102244317-102271597 Sample_02_0063 Skin Keratinocytes 891 4 712 17 1 1 0 BIRC3
SE_02_143500189 chr11:102244371-102288024 Sample_02_1435 Trophoblast trophoblast stem cells_MSX2_KD 189 10 1195 35 2 22 0 BIRC3
SE_02_060300210 chr11:102244446-102270561 Sample_02_0603 Mammary gland MCF10A_p63shRNA_Nutlin3A 210 6 682 17 1 1 0 BIRC3
SE_02_059700250 chr11:102244576-102270881 Sample_02_0597 Mammary gland MCF10A_Nutlin3A 250 6 686 16 1 1 0 BIRC3
SE_02_112000383 chr11:102244599-102270664 Sample_02_1120 Neonatal foreskin keratinocytes_CTR 383 8 680 16 1 1 0 BIRC3
SE_02_066101057 chr11:102244660-102280693 Sample_02_0661 Mammary gland MCF10DCIS-TetTCF7 1057 11 982 28 1 22 0 BIRC3
SE_02_071900761 chr11:102244796-102288063 Sample_02_0719 Pancreas SUIT2_TP63dN_DOX 761 8 1187 34 2 22 0 BIRC3
SE_02_113100451 chr11:102244880-102270946 Sample_02_1131 Pancreas T3M4 wt 451 10 679 16 1 1 0 BIRC3
SE_02_112100978 chr11:102252362-102271048 Sample_02_1121 Neonatal foreskin keratinocytes_Mi2KD 978 8 493 14 1 1 0 BIRC3
SE_02_130500567 chr11:102253225-102269457 Sample_02_1305 Pancreas Gemcitabine resistant L3.6pl 567 5 433 13 1 0 0 BIRC3
SE_02_071600355 chr11:102253585-102314816 Sample_02_0716 Pancreas SUIT2_GFP 355 13 1722 88 2 23 37 BIRC2,BIRC3
SE_02_092900937 chr11:102255418-102288014 Sample_02_0929 Mid-gestation placenta trophoblast__CytT 937 15 903 29 2 22 0 BIRC3
SE_02_049401042 chr11:102275427-102281938 Sample_02_0494 Islets differentiated hESCs Late pancreatic progenitor cells 1042 3 197 10 0 19 0 BIRC3
SE_02_047500461 chr11:102293268-102315215 Sample_02_0475 Induced hepatocyte-like cells hepatocyte-like cells 461 8 625 52 0 0 37 BIRC2,BIRC3
SE_02_059500083 chr11:102300574-102315388 Sample_02_0595 Mammary gland MCF10A_scrshRNA_Nutlin3A 83 8 399 24 0 0 37 BIRC2,BIRC3
SE_02_059700384 chr11:102300626-102314677 Sample_02_0597 Mammary gland MCF10A_Nutlin3A 384 6 390 24 0 0 37 BIRC2,BIRC3
SE_02_016700376 chr11:102304692-102314925 Sample_02_0167 Mammary gland HCC1954_LCC2 376 2 274 15 0 0 37 BIRC3,BIRC2
SE_01_004500926 chr11:102304906-102315291 Sample_01_0045 Mammary gland mammary-epithelial-cell 926 3 273 15 0 0 37 BIRC3,BIRC2
SE_02_070400478 chr11:102305356-102313717 Sample_02_0704 Pancreas HPAFII WT 478 4 235 14 0 0 11 BIRC2,BIRC3
SE_02_135200536 chr11:102339437-102348955 Sample_02_1352 Mammary gland MDA-MB-231-Erbeta_E2 536 3 241 9 0 11 230 BIRC2,BIRC3
SE_02_060200683 chr11:102339694-102349417 Sample_02_0602 Mammary gland MCF10A_p63shRNA_DMSO 683 3 244 11 0 11 243 BIRC2,BIRC3
SE_02_048101243 chr11:102340122-102351051 Sample_02_0481 Mammary gland MDA-MB231 1243 5 276 12 0 30 371 BIRC2,BIRC3
SE_02_143700992 chr11:102340178-102351062 Sample_02_1437 Liver LSEC-TNF 992 3 275 12 0 30 374 BIRC2,BIRC3
SE_02_135400357 chr11:102340958-102349412 Sample_02_1354 Mammary gland MDA-MB-231-Erbeta_E2_TNFa 357 3 211 10 0 11 243 BIRC2,BIRC3
SE_02_152201152 chr11:102341005-102349835 Sample_02_1522 Skin A375 RTKi 1152 2 221 11 0 11 264 BIRC2,BIRC3
SE_02_049901554 chr11:102341418-102361856 Sample_02_0499 Fetal lung IMR90 IR Senescence 1554 5 546 28 0 32 377 BIRC2,BIRC3
SE_02_113800764 chr11:102341423-102350229 Sample_02_1138 Retinal Pigmented Epithelial RPE1-prometaphase 764 2 222 11 0 17 298 BIRC2,BIRC3
SE_02_041900985 chr11:102341526-102349809 Sample_02_0419 Pectoralis major muscle LHCN-M2_nodox 985 4 204 11 0 11 264 BIRC2,BIRC3
SE_02_113900787 chr11:102341571-102350768 Sample_02_1139 Retinal Pigmented Epithelial RPE1-anaphase/telophase 787 4 230 11 0 24 352 BIRC2,BIRC3
SE_02_017300771 chr11:102342684-102350349 Sample_02_0173 Lung IMR-90_senescent 771 1 195 9 0 18 309 BIRC2,BIRC3
SE_02_029400719 chr11:102342987-102351439 Sample_02_0294 Pancreatic L3-6_DMSO 719 1 215 10 0 30 377 BIRC2,BIRC3
SE_02_005400607 chr11:102343057-102349645 Sample_02_0054 Lung IMR-90_DMSO_1 607 1 163 9 0 11 255 BIRC2,BIRC3
SE_02_005500766 chr11:102343177-102349741 Sample_02_0055 Lung IMR-90_Nutlin-3a 766 1 160 8 0 11 262 BIRC2,BIRC3
SE_02_061900341 chr11:102343230-102351761 Sample_02_0619 Head and Neck HPV+ HNSCC_SCC-047 341 3 224 9 0 30 377 BIRC2,BIRC3
SE_02_082400011 chr11:102343313-102347093 Sample_02_0824 Stomach LMSU 11 1 85 2 0 10 21 BIRC2,BIRC3
SE_02_085800743 chr11:102343313-102348459 Sample_02_0858 Glioblastoma Glioblastoma neurosphere cell_HF-3177 743 1 132 5 0 10 191 BIRC2,BIRC3
SE_02_072700683 chr11:102343321-102348647 Sample_02_0727 Fetal lung IMR90_Etoposide 683 2 141 5 0 10 198 BIRC2,BIRC3
SE_02_049100185 chr11:102343321-102349280 Sample_02_0491 Pharyng Detroit 562-Control 185 2 148 7 0 11 234 BIRC2,BIRC3
SE_02_044800480 chr11:102343380-102348422 Sample_02_0448 Bone MNNG 480 2 128 4 0 10 191 BIRC2,BIRC3
SE_02_055700404 chr11:102343411-102349012 Sample_02_0557 iPSCs WT hiPSC#1 404 1 140 4 0 11 218 BIRC2,BIRC3
SE_02_156901109 chr11:102343881-102349117 Sample_02_1569 Endothelial Endothelial cells 1109 1 131 4 0 11 223 BIRC2,BIRC3
SE_02_071500275 chr11:102343956-102349666 Sample_02_0715 Pancreas SUIT2_TP63dN 275 2 144 7 0 11 256 BIRC2,BIRC3
SE_02_061500595 chr11:102343978-102349373 Sample_02_0615 Liposarcoma liposarcoma cells_MLS402 595 1 135 6 0 11 239 BIRC2,BIRC3
SE_02_094600619 chr11:102344013-102348577 Sample_02_0946 Tongue HN12 619 2 123 4 0 10 193 BIRC2,BIRC3
SE_02_055600499 chr11:102344175-102348675 Sample_02_0556 iPSCs BOFS hiPSC cl1 499 1 120 4 0 10 204 BIRC2,BIRC3
SE_02_135100740 chr11:102344221-102349099 Sample_02_1351 Mammary gland MDA-MB-231-Erbeta_vehicle 740 1 120 4 0 11 223 BIRC2,BIRC3
SE_02_126000791 chr11:102344325-102348385 Sample_02_1260 Bone Im-GCT-3504_G34W-repair_4F5 791 1 104 4 0 10 191 BIRC2,BIRC3
SE_02_135300571 chr11:102344423-102348855 Sample_02_1353 Mammary gland MDA-MB-231-Erbeta_TNFa 571 1 114 4 0 11 212 BIRC2,BIRC3
SE_02_071900543 chr11:102344477-102350171 Sample_02_0719 Pancreas SUIT2_TP63dN_DOX 543 1 142 7 0 17 294 BIRC2,BIRC3
SE_02_000700037 chr11:102344503-102348414 Sample_02_0007 Cervical cervical-cancer_vector 37 2 100 4 0 10 191 BIRC2,BIRC3
SE_02_094800037 chr11:102344656-102349250 Sample_02_0948 Pharyng Detroit562 37 1 115 6 0 11 232 BIRC2,BIRC3
SE_02_130901128 chr11:102344676-102348845 Sample_02_1309 Artery Pulmonary artery endothelial cells_Control 1128 1 108 3 0 10 212 BIRC2,BIRC3
SE_02_064900612 chr11:102344730-102348727 Sample_02_0649 Tracheobronchial epithelial HTBE_H3N2_06h 612 1 107 3 0 10 209 BIRC2,BIRC3
SE_02_093801169 chr11:102344731-102348679 Sample_02_0938 Retinal Pigmented Epithelial RPE190_TnT 1169 1 107 3 0 10 206 BIRC2,BIRC3
SE_02_064801331 chr11:102344801-102348471 Sample_02_0648 Tracheobronchial epithelial HTBE_H3N2_03h 1331 1 97 3 0 10 191 BIRC2,BIRC3
SE_02_145200995 chr11:102344854-102350259 Sample_02_1452 Arter pulmonary arterial smooth muscle cells_PAH2_sictrl 995 2 139 6 0 17 300 BIRC2,BIRC3
SE_02_064501505 chr11:102345130-102348947 Sample_02_0645 Tracheobronchial epithelial HTBE_H1N1_18h 1505 1 98 3 0 11 215 BIRC2,BIRC3
SE_02_000600079 chr11:102345359-102348816 Sample_02_0006 Cervical cervical-cancer_parental 79 2 91 3 0 10 211 BIRC2,BIRC3
SE_02_042000335 chr11:102345369-102391793 Sample_02_0420 Pectoralis major muscle LHCN-M2_dox_6h 335 7 1231 80 2 50 573 BIRC2,BIRC3
Genomic distribution of SEs associated with BIRC3
Genome Browser

The strength of the tissue affected by the gene

Expression of BIRC3

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)