SEdb 2.0
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Gene overview

Strategies/Algorithm: overlap Ensembl ID: ENSG00000105127
Gene: AKAP8 Gene type: protein_coding
Strand: - External links:
Genomic region: chr19:15353385-15379798 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_074600098 chr19:15238597-15360896 Sample_02_0746 Embryo ES derived primitive cardiomyocite_day15 98 45 3497 80 2 439 3443 AKAP8,BRD4,EPHX3,NOTCH3
SE_02_103500018 chr19:15295693-15439025 Sample_02_1035 Mammary gland HCC70_Vehicle 18 60 3965 132 30 652 5424 AKAP8L,AKAP8,WIZ,PGLYRP2,MIR1470,BRD4,RASAL3
SE_02_039600740 chr19:15354715-15381031 Sample_02_0396 Skin NHEK-D 740 6 888 27 11 93 1678 AKAP8,AKAP8L
SE_02_050600592 chr19:15355666-15383628 Sample_02_0506 Esophagus TE5_1 592 9 903 29 12 91 1549 AKAP8L,AKAP8
SE_02_051700595 chr19:15355700-15383627 Sample_02_0517 Esophagus TE5 595 9 900 29 12 91 1549 AKAP8L,AKAP8
SE_02_050500686 chr19:15357738-15382494 Sample_02_0505 Esophagus KYSE70_1 686 8 821 27 12 91 1549 AKAP8L,AKAP8
SE_02_051600697 chr19:15357738-15382494 Sample_02_0516 Esophagus KYSE70 697 8 821 27 12 91 1549 AKAP8L,AKAP8
SE_02_088600363 chr19:15358128-15433918 Sample_02_0886 Skin foreskin_ p63KLF4 363 20 2143 85 28 516 4662 AKAP8L,AKAP8,WIZ,PGLYRP2,MIR1470,RASAL3
SE_02_068300233 chr19:15358773-15433728 Sample_02_0683 Lung DMS114 233 26 2123 84 27 516 4659 AKAP8L,AKAP8,WIZ,PGLYRP2,MIR1470,RASAL3
SE_02_146800035 chr19:15358993-15433449 Sample_02_1468 Blood HUDEP-2_WT 35 14 2110 84 27 515 4636 AKAP8L,AKAP8,WIZ,PGLYRP2,MIR1470,RASAL3
SE_02_046100439 chr19:15359167-15379900 Sample_02_0461 Blood MV-4-11-B cells 439 5 736 24 10 83 1265 AKAP8,AKAP8L
SE_01_008401582 chr19:15360009-15380953 Sample_01_0084 Spleen spleen 1582 5 734 23 10 88 1499 AKAP8,AKAP8L
SE_02_133200302 chr19:15362569-15380749 Sample_02_1332 Blood Monomac6_CTRL 302 5 623 19 8 79 1235 AKAP8L,AKAP8
SE_02_081601166 chr19:15362665-15380884 Sample_02_0816 Ovary Clear cell ovarian cancer 1166 6 626 19 8 79 1244 AKAP8L,AKAP8
SE_02_143201248 chr19:15363045-15380816 Sample_02_1432 Bone A673 STAG2 WT 1248 7 614 18 8 79 1244 AKAP8L,AKAP8
SE_02_138200347 chr19:15364677-15415101 Sample_02_1382 Pancreas Pancreatic cancer cells_Triptolide 347 26 1404 59 21 259 2363 AKAP8L,AKAP8,MIR1470,RASAL3,WIZ
SE_02_104800673 chr19:15364835-15404877 Sample_02_1048 Peripheral blood CD4+ cell_UNTREATED 673 9 1154 47 17 251 2307 AKAP8L,AKAP8,MIR1470,WIZ
SE_02_138100453 chr19:15365627-15382144 Sample_02_1381 Pancreas Pancreatic cancer cells_DMSO 453 11 574 17 9 79 1244 AKAP8L,AKAP8
SE_02_025600594 chr19:15369194-15381209 Sample_02_0256 Peripheral blood MV411 594 2 422 8 6 57 1089 AKAP8,AKAP8L
SE_02_046300102 chr19:15370276-15379776 Sample_02_0463 Blood OCI-AML3 cells 102 4 354 8 6 41 717 AKAP8,AKAP8L
SE_02_147100533 chr19:15370720-15388897 Sample_02_1471 Blood Outgrowth Endothelia BOEC 533 3 549 18 8 51 964 AKAP8L,AKAP8
SE_02_033700262 chr19:15370843-15381121 Sample_02_0337 Haematopoietic and lymphoid tissue MV411_untreat 262 2 368 7 6 51 964 AKAP8,AKAP8L
SE_02_133100775 chr19:15370861-15380642 Sample_02_1331 Blood Molm13_CTRL 775 2 354 7 6 51 930 AKAP8L,AKAP8
SE_02_034700419 chr19:15370977-15380841 Sample_02_0347 Blood AML11 419 3 354 7 6 51 964 AKAP8,AKAP8L
SE_02_138300147 chr19:15371052-15433270 Sample_02_1383 Pancreas Pancreatic cancer cells_THZ1 147 28 1703 67 23 476 4077 AKAP8L,AKAP8,WIZ,PGLYRP2,MIR1470,RASAL3
SE_02_055500899 chr19:15371796-15380954 Sample_02_0555 Other HAP1_WT 899 5 335 7 6 51 958 AKAP8L,AKAP8
SE_02_057700447 chr19:15372035-15380747 Sample_02_0577 Blood MOLM13_empty 447 3 318 7 6 49 914 AKAP8L,AKAP8
SE_02_057400530 chr19:15372085-15380843 Sample_02_0574 Blood MOLM-13_sgNeg2 530 3 315 7 6 49 908 AKAP8L,AKAP8
SE_02_058100436 chr19:15372130-15380779 Sample_02_0581 Blood MOLM13_empty_HG 436 4 313 7 6 49 898 AKAP8L,AKAP8
SE_02_057500732 chr19:15372139-15379945 Sample_02_0575 Blood MOLM13_sgLKB1e2 732 3 301 7 6 44 669 AKAP8,AKAP8L
SE_02_058200417 chr19:15372162-15380823 Sample_02_0582 Blood MOLM13_SIK3TQ_HG 417 3 313 7 6 49 894 AKAP8L,AKAP8
SE_02_057800712 chr19:15372269-15379892 Sample_02_0578 Blood MOLM-13_sgSIK3e4 712 4 293 7 6 44 624 AKAP8,AKAP8L
SE_02_019400343 chr19:15373165-15381269 Sample_02_0194 Kidney Patient_x750T 343 1 269 7 5 35 724 AKAP8,AKAP8L
SE_02_098901348 chr19:15373373-15417276 Sample_02_0989 Kidney kidney cortex_WT 1348 19 1143 55 19 212 1800 AKAP8L,AKAP8,MIR1470,RASAL3,WIZ
SE_02_096800440 chr19:15373619-15380851 Sample_02_0968 Brain H3.3K27M_pcGBM2p18_cells 440 2 239 7 5 32 640 AKAP8L,AKAP8
SE_02_142400314 chr19:15373670-15379783 Sample_02_1424 Haematopoietic and lymphoid tissue bone marrow K562_Triptolide_4h 314 3 218 7 5 22 366 AKAP8,AKAP8L
SE_02_141600895 chr19:15373789-15381032 Sample_02_1416 Brain SF9402 895 1 241 7 5 32 592 AKAP8L,AKAP8
SE_02_081800477 chr19:15373919-15433740 Sample_02_0818 Ovary High-grade serous ovarian cancer 477 17 1595 67 22 452 3670 AKAP8L,AKAP8,WIZ,PGLYRP2,MIR1470,RASAL3
SE_00_003901131 chr19:15374167-15380912 Sample_00_0039 Spleen spleen_3y 1131 2 216 7 5 23 499 AKAP8,AKAP8L
SE_02_035900858 chr19:15374506-15381159 Sample_02_0359 Colon Colo741 858 2 211 7 5 23 464 AKAP8,AKAP8L
SE_02_152000766 chr19:15374944-15387914 Sample_02_1520 Umbilical vein HUVEC_Notch1kd_IL1beta 766 3 346 16 6 18 395 AKAP8L,AKAP8
SE_02_088401043 chr19:15375847-15381482 Sample_02_0884 Colon LoVo 1043 1 158 0 0 18 395 AKAP8L,AKAP8
SE_02_092901059 chr19:15376748-15379779 Sample_02_0929 Mid-gestation placenta trophoblast__CytT 1059 1 90 0 0 8 133 AKAP8,AKAP8L
SE_02_126900811 chr19:15376795-15380792 Sample_02_1269 Bone Im-GCT-4072_G34W-repair_WT_A4 811 1 108 0 0 18 394 AKAP8L,AKAP8
SE_02_064500912 chr19:15376842-15381028 Sample_02_0645 Tracheobronchial epithelial HTBE_H1N1_18h 912 3 114 0 0 18 390 AKAP8L,AKAP8
SE_02_135101094 chr19:15376916-15380797 Sample_02_1351 Mammary gland MDA-MB-231-Erbeta_vehicle 1094 1 108 0 0 18 375 AKAP8L,AKAP8
SE_02_145201286 chr19:15377161-15380663 Sample_02_1452 Arter pulmonary arterial smooth muscle cells_PAH2_sictrl 1286 1 97 0 0 15 290 AKAP8L,AKAP8
SE_02_085800888 chr19:15377165-15380982 Sample_02_0858 Glioblastoma Glioblastoma neurosphere cell_HF-3177 888 1 106 0 0 15 324 AKAP8L,AKAP8
SE_02_132201038 chr19:15377201-15380822 Sample_02_1322 Connective Tissue HT1080_WT 1038 1 101 0 0 14 322 AKAP8L,AKAP8
SE_02_158401160 chr19:15377220-15380837 Sample_02_1584 Brain U87 GBM_Mock 1160 1 101 0 0 14 322 AKAP8L,AKAP8
SE_02_073900613 chr19:15377239-15434012 Sample_02_0739 Blood Nalm6 613 10 1468 60 17 439 3435 AKAP8L,AKAP8,WIZ,PGLYRP2,MIR1470,RASAL3
SE_02_146700085 chr19:15377453-15433729 Sample_02_1467 Blood HUDEP-2_LRFKO 85 13 1455 60 17 439 3435 AKAP8L,AKAP8,WIZ,PGLYRP2,MIR1470,RASAL3
SE_02_143301151 chr19:15377633-15380854 Sample_02_1433 Bone A673 STAG2 null 1151 1 87 0 0 14 322 AKAP8L,AKAP8
SE_02_074600190 chr19:15377651-15433174 Sample_02_0746 Embryo ES derived primitive cardiomyocite_day15 190 23 1439 60 17 439 3435 AKAP8L,AKAP8,WIZ,PGLYRP2,MIR1470,RASAL3
SE_02_146600369 chr19:15377661-15381869 Sample_02_1466 Blood HUDEP-2_BCL11AKO 369 1 108 0 0 14 322 AKAP8L,AKAP8
SE_02_102600561 chr19:15377749-15380854 Sample_02_1026 Esophagus KYSE200 561 1 85 0 0 14 322 AKAP8L,AKAP8
Genomic distribution of SEs associated with AKAP8
Genome Browser

The strength of the tissue affected by the gene

Expression of AKAP8

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)